There are five Pastoral Regions in the Archdiocese of Los Angeles.  They were established in 1986.​

Our Lady of the Angels

• Area: Downtown and central Los Angeles west to Malibu, south to LAX.
• Regional Bishop: Bishop Edward W. Clark
• Deaneries: 13-16
  
• Parishes: 78
• High Schools: 11
• Hospitals: 5
• Missions: 5
  Learn More about OLAPR.

San Fernando

• Area: San Fernando, Santa Clarita and Antelope Valleys
• Regional Bishop: Bishop Alejandro "Alex" Aclan
• Deaneries: 5-8
  
• Parishes: 55
• High Schools: 12
• Hospitals: 2
• Missions: 5
  Learn More about SFPR.
  

San Gabriel

• Area: East Los Angeles through San Gabriel and Pomona Valleys
• Regional Bishop: Bishop David G. O'Connell
• Deaneries: 9-12
  
• Parishes: 66
• High Schools: 13
• Hospitals: 1
• Missions: 2
  Learn More about SGPR.
  

San Pedro

• Area: Long Beach and Southern Los Angeles County
• Regional Bishop: Bishop Marc Trudeau​
  
• Parishes: 67
• High Schools: 8
• Hospitals: 4
• Missions: 1
  Learn More about SPPR
  

Santa Barbara

• Area: Santa Barbara and Ventura Counties
• Regional Bishop: Bishop Robert E. Barron
• Deaneries: 1-4
• Parishes: 37
• High Schools: 6
• Hospitals: 4
• Missions: 5
  Learn More about SBPR